Publications

For the lastest publications: PubMed

Cole ES, Anderson PC, Fulton RB, Majerus ME, Rooney MG, Savage JM, Chalker D, Honts J, Welch ME, Wentland AL, Zweifel E, Beussman DJ. (2008) A proteomics approach to cloning fenestrin from the nuclear exchange junction of Tetrahymena. J Eukaryot Microbiol. 55(4):245-56.

Malone CD, Falkowska KA, Li AY, Galanti SE, Kanuru RC, LaMont EG, Mazzarella KC, Micev AJ, Osman MM, Piotrowski NK, Suszko JW, Timm AC, Xu MM, Liu L, Chalker DL. (2008) Nucleus-specific importin alpha proteins and nucleoporins regulate protein import and nuclear division in the binucleate Tetrahymena thermophila. Eukaryot Cell. 7:1487-99.

Charles H. Rexer and Douglas L. Chalker. (2007) Lia1p, a Novel Protein Required during Nuclear Differentiation for Genome-Wide DNA Rearrangements in Tetrahymena thermophila. Eukaryotic Cell 6(8):1320-1329.

M.-C. Yao, C.-H. Yao, L.M. Halasz, P. Fuller, C.H. Rexer, S.H. Wang, R. Jain, R.S. Coyne and D.L. Chalker. (2007) Identification of novel chromatin-associated proteins involved in programmed genome rearrangements in Tetrahymena. J. Cell. Sci 120(9): 1978-89.

Christina A. Kowalczyk, Alissa M. Anderson, Maria Arce-Larreta, Douglas L. Chalker (2006) The germ line limited M element of Tetrahymena is targeted for elimination from the somatic genome by a homology-dependent mechanism Nucl Acids Res. 34(20):5778-5789.

Malone C.D., A. M. Anderson, J. A. Motl, C. H. Rexer, and  D. L. Chalker. (2005)

Germline transcripts are processed by a Dicer-like protein that is essential for developmentally programmed genome rearrangements of Tetrahymena thermophila. Mol. Cell. Biology 25(20):9151-64.

Chalker, D. L., P. Fuller, and M.-C. Yao.  (2005). RNA mediates effective communication between parental and developing genomes during Tetrahymena nuclear differentiation.  Genetics 169: 149-160. (PDF)

Chalker, D. L. and M.-C. Yao. (2001). Non-genic, bio-directional transcription precedes and may promote developmental DNA deletion in Tetrahymena thermophila. Genes & Dev. 15: 1287-1298. (PDF)

Yao, M.C., Duharcourt, S., and Chalker, D.L. (2001). Genome-wide rearrangements of DNA in Ciliates. In Mobile DNA II, (ed. N. Craig, R. Craigie, M. Gellert and A. Lambowitz), pp 730-758. Academic Press, New York, NY.

Chalker, D.L., LaTerza, A., Wilson, A., Kroenke, C.D., and M.-C. Yao. (1999) Flanking regulatory sequences of the Tetrahymena thermophila R deletion element determine the boundaries of rearrangement. Mol. Cell. Biol. 19:5631-5641. (PDF)

Chalker, D.L., Ward, J.G., Randolph, C., and M. –C. Yao. (1999) Microinjection of Tetrahymena thermophila. Methods Cell Biol. 62: 469-484.

Chalker, D.L. and M.-C. Yao. (1996). Non-Mendelian, Heritable blocks to DNA rearrangement are induced by loading the somatic nucleus of Tetrahymena thermophila with germ line-limited DNA. Mol. Cell. Biol. 16:3658-3667. (PDF)

Coyne, R. S., Chalker, D.L. and M.-C. Yao. (1997). Genome downsizing during ciliate development: nuclear division of labor through chromosome restructuring. Ann. Rev. Genet. 30: 557-578.